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00162_Field_SRC.c06.A.12.txt
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1997-01-28
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• Tumor tissue tests, including hormone receptors, DNA and other protein markers with potential diagnostic
and prognostic value.
Imaging
• Mammography is helpful in evaluating a suspicious mass, especially if it is new or persistent. It is also useful
in women whose breasts are large and difficult to examine or who have had implants. Mammography is also
used to locate precisely the position and extent of a known tumor. A standard two-view mammogram and
specialized views, including magnified images, can provide vital information, but mammography is not a
definitive diagnostic test since 10 to 15 percent of cancers are not detectable by this technique. A suspicious
palpable mass should be biopsied even if mammography does not show cancer.
• Mammograms may detect an abnormality elsewhere in the same or opposite breast. These images may show
microcalcifications suspicious for cancer (even if no mass is palpable) or a smaller, non-palpable but still
suspicious mass. In this situation, a biopsy must be done, usually guided by mammography, to determine
whether the lesion is cancer.
• Mammography may also be used to evaluate women with precancerous breast conditions, to evaluate yearly
the opposite breast of women with known breast cancer (as there is a higher risk of developing cancer there)
and to evaluate women with metastatic adenocarcinoma from an unknown primary source. Sometimes the
primary source is a hidden breast cancer. This last point is especially important because breast cancer may
respond to chemotherapy or hormonal therapy not used to treat other forms of metastatic cancer.